Antler is the secondary sexual characteristic of deer, which develops on the forehead at puberty. It is the only organ that can be regenerated entirely in mammals. Therefore, it is often used as a research model in the field of organ regeneration and wound repair. Many growth factors and proteins play an active role throughout the developmental process of antler regeneration. With the rapid development of sequencing technology, more and more noncoding RNAs (ncRNAs) have been discovered, and the relationship between ncRNA and antler regeneration has gradually become clear. This paper focuses on the research progress of several ncRNAs (including miRNA and lncRNA) in deer antler tissues, which are helpful to reveal the molecular mechanism of deer antler regeneration at the molecular level. Copyright © 2022 Yipu Wang and Wei Hu.
Yipu Wang, Wei Hu. Progress of Noncoding RNA Regulating the Growth and Development of Antler Tissue Research. BioMed research international. 2022;2022:3541577
PMID: 35909491
View Full Text