Diamond-Blackfan anaemia with iron overload: A serious issue.

Transfusion-dependent Diamond-Blackfan anaemia (DBA) patients rapidly develop iron overload and frequently experience cardiac complications. The report by Lecornec and colleagues offers useful details on indications and the management of deferiprone, a highly efficient chelator in removing excess cardiac iron but associated with a high risk of agranulocytosis in DBA patients. Commentary on: Nicolas Lecornec and colleagues: Agranulocytosis in patients with Diamond-Blackfan anaemia treated with deferiprone for post-transfusion iron overload: A retrospective study of the French DBA cohort. British Journal of Haematology 2022.© 2022 British Society for Haematology and John Wiley & Sons Ltd.

Citation

Paola Quarello, Ugo Ramenghi, Franca Fagioli. Diamond-Blackfan anaemia with iron overload: A serious issue. British journal of haematology. 2022 Aug 05

PMID: 35929529

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