A robust [11C]acetate synthesis on a TRACERLab FX C pro module.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2022 Oct

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Carbon-11 labelled acetate ([11C]acetate) is a radiotracer of importance in clinical practice as well as in preclinical research. The TRACERLab FX C Pro Synthesizer can be used this sensitive carboxylation reaction. Starting from 11 GBq [11C]CO2, we were able to isolate about 3 GBq [11C]acetate after only 20 min reaction time (yield 56 ± 7%, n = 10). Copyright © 2022. Published by Elsevier Ltd.

Citation

Jan Wenz, Felix Arndt, Samuel Samnick. A robust [11C]acetate synthesis on a TRACERLab FX C pro module. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2022 Oct;188:110356