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Amide bond hydrolysis of peptoids.
Chemical communications (Cambridge, England) 2022 Sep 01Sizes of these terms reflect their relevance to your search.
Incorporating a chiral non-coordinating substitution at the N-terminal end within peptoids facilitates regio-selective amide bond hydrolysis mediated by a transition metal ion and/or an acidic buffer as evident by X-ray crystallographic analysis, supported by ESI-MS. This opens up a new direction for peptidomimetic compounds towards future application in chemistry, biology and medicine.
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Pritam Ghosh, Guilin Ruan, Natalia Fridman, Galia Maayan. Amide bond hydrolysis of peptoids. Chemical communications (Cambridge, England). 2022 Sep 01;58(71):9922-9925
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PMID: 35979818
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