Hypergranulation over a meshed split-thickness skin graft, a complication of negative-pressure wound therapy: a case report.

We present a case of a rare complication of negative-pressure wound therapy (NPWT) wherein there was fixation of a meshed split-thickness skin graft (STSG), suspected as a failure by hypergranulation. However, the meshed STSG was integrated within 5 days of NPWT cessation. A 22-year-old Asian man sustained 25% total-body-surface-area flame burns. After multiple operations, an ulcer was present on the proximal left thigh. On day 37 after admission, the ulcer was debrided, and an 11/1000-inch (0.28 mm) skin graft was taken from the ipsilateral thigh and meshed, using a 1:1.5 ratio. NPWT was applied to the donor and recipient sites with a continuous negative pressure of 125 mmHg. On day 43, NPWT was discontinued. The skin grafts were not identified on the surface of the granulation tissue. With topical ointment therapy, rapid epithelialization of the ulcer was observed as the granulation tissue regressed. On day 48, the recipient site had completely epithelialized. The hypergranulation tissue rarely covered the meshed STSGs when the grafts were fixed by NPWT. In that case, immediate debridement should be avoided, and conservative treatment should be initiated. © 2022. The Author(s).

Citation

Masato Shiba, Tomoaki Doi, Hideshi Okada, Ryo Kamidani, Genki Yoshimura, Keigo Kusuzawa, Fuminori Yamaji, Tomotaka Miura, Hideaki Oiwa, Yosuke Mizuno, Ryu Yasuda, Tetsuya Fukuta, Yuichiro Kitagawa, Takahito Miyake, Takahiro Yoshida, Shozo Yoshida, Shinji Ogura. Hypergranulation over a meshed split-thickness skin graft, a complication of negative-pressure wound therapy: a case report. Journal of medical case reports. 2022 Aug 30;16(1):335

Mesh Tags

PMID: 36042464

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