Methionine restriction forces Epstein-Barr virus out of latency.

Sriraksha Bharadwaj Kashyap, Racheal Mulondo, Peter J Mullen

Cell metabolism 2022 Sep 06

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EBV gene expression is repressed during viral latency to prevent an immune response, but it is not known how metabolism contributes to this silencing. In this issue of Cell Metabolism, Guo et al. describe how methionine restriction reactivates the expression of EBV genes, offering new therapeutic approaches against EBV-driven diseases. Copyright © 2022 Elsevier Inc. All rights reserved.

Citation

Sriraksha Bharadwaj Kashyap, Racheal Mulondo, Peter J Mullen. Methionine restriction forces Epstein-Barr virus out of latency. Cell metabolism. 2022 Sep 06;34(9):1229-1231