How cells spatially organize their plasma membrane, cytoskeleton, and cytoplasm remains a central question for cell biologists. In this issue of JCB, Calvi et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202201048) identify PP1 phosphatases as key regulators of C. elegans anterior-posterior polarity, by counterbalancing aPKC-mediated phosphorylation of PAR-2. © 2022 Barros-Carvalho and Morais-de-Sa.
André Barros-Carvalho, Eurico Morais-de-Sá. Balancing cell polarity PARts through dephosphorylation. The Journal of cell biology. 2022 Sep 19;221(10)
PMID: 36121422
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