Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review.

Yan Yang, Zhengtao Chen, Xiaoyan Zhao, Hongyan Xie, Lian Du, Hong Gao, Chunguang Xie

Frontiers in endocrinology 2022

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Obesity-insulin resistance-β-cells apoptosis" is an important trilogy of the pathogenesis of type 2 diabetes. With the global pandemic of obesity and diabetes, continuous research and development of new drugs focuses on the prevention of the pathological progress of these diseases. According to a recent study, the natural product kaempferol has excellent antidiabetic effects. Therefore, this review comprehensively summarized the frontier studies and pharmacological mechanisms of kaempferol in the treatment of diabetes. The successful research and development of kaempferol may yield a significant leap in the treatment of diabetes and its complications. Copyright © 2022 Yang, Chen, Zhao, Xie, Du, Gao and Xie.

Citation

Yan Yang, Zhengtao Chen, Xiaoyan Zhao, Hongyan Xie, Lian Du, Hong Gao, Chunguang Xie. Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review. Frontiers in endocrinology. 2022;13:990299