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A 38-year-old man with von Hippel-Lindau (VHL) disease and a history of renal cell carcinoma presented with a 2-month history of recurrent epistaxis. MRI revealed a microcystic tumor in the left ethmoid sinus with strong contrast enhancement. 18 F-FDG PET/CT showed FDG uptake (SUV max , 4.2) in the lesion. Under the suspicion of renal cell carcinoma metastasis, the patient underwent 2 surgical resections. However, based on the morphological and immunohistochemical findings, the patient was finally diagnosed with a VHL-associated microcystic adenoma of the ethmoid sinus, which is an extremely rare tumor that occurs in VHL disease. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

Citation

Suzune Tsukamoto, Sho Koyasu, Akihiko Sugimoto, Mami Matsunaga, Yuji Nakamoto. A Von Hippel-Lindau Disease-Associated Microcystic Adenoma of the Ethmoid Sinus Mimicking Metastatic Clear Cell Renal Cell Carcinoma. Clinical nuclear medicine. 2023 Feb 01;48(2):194-196

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PMID: 36179325

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