Correlation Engine 2.0
Clear Search sequence regions

  • bone bones (1)
  • fast (1)
  • humans (1)
  • phase (3)
  • signal (2)
  • Sizes of these terms reflect their relevance to your search.

    Extend fast, two-dimensional (2D) methods of bound and pore water mapping in bone to arbitrary slice orientation. To correct for slice profile artifacts caused by gradient errors of half pulse 2D ultra-short echo time (UTE), we developed a library of predistorted gradient waveforms that can be used to interpolate optimized gradient waveforms for 2D UTE slice selection. We also developed a method to estimate and correct for a bulk phase difference between the two half pulse excitations used for 2D UTE signal excitation. Bound water images were acquired in three healthy subjects with adiabatic inversion recovery prepared 2D UTE, while pore water images were acquired after short-T2 signals were suppressed with double adiabatic inversion recovery preparation. The repeatability of bound and pore water imaging with 2D UTE was tested by repeating acquisitions after repositioning. The library-based interpolation of optimized slice select gradient waveforms combined with the method to estimate bulk phase between two excitations provided compact slice profiles for half pulse excited 2D UTE. Quantitative bound and pore water values were highly repeatable-the pooled SD of bound water across all three subjects was 0.38 mol 1 $$ {}^1 $$ H/L, while pooled SD of pore water was 0.30 mol 1 $$ {}^1 $$ H/L. Fast, quantitative, 2D UTE-based bound and pore water images can be acquired at arbitrary oblique orientations after correcting for errors in the slice select gradient waveform and bulk phase shift between the two half acquisitions. © 2022 International Society for Magnetic Resonance in Medicine.


    Kevin D Harkins, Thammathida Ketsiri, Jeffry S Nyman, Mark D Does. Fast bound and pore water mapping of cortical bone with arbitrary slice oriented two-dimensional ultra-short echo time. Magnetic resonance in medicine. 2023 Feb;89(2):767-773

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 36226656

    View Full Text