Replacing petroleum-based fuels in high-power sectors like aviation and rocketry is a major sustainability challenge. Polycyclopropanated hydrocarbons provide excellent fuel characteristics for these applications, but their synthesis is challenging. Cruz-Morales et al. demonstrated microbial production of a range of polycyclopropanated 'fuelimycins' based on an unusual iterative polyketide synthase (iPKS). Copyright © 2022 Elsevier Ltd. All rights reserved.
Benjamin M Woolston. Engineering bacteria for production of sustainable polycyclopropanated jet fuel alternatives. Trends in biotechnology. 2022 Dec;40(12):1399-1400
PMID: 36302713
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