Complete disappearance of pulmonary rheumatoid nodules after long term rituximab treatment: case report.

Beatriz Frade-Sosa, Ana Belen Azuaga, Virginia Ruiz-Esquide, José A Gómez-Puerta, Raimon Sanmarti

Rheumatology international 2023 Mar

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The natural history of pulmonary rheumatoid nodules in rheumatoid arthritis remains uncertain. We present a case of a patient with rheumatoid arthritis with pulmonary rheumatoid nodules diagnosed while receiving etanercept in whom pulmonary nodules resolved completely after 5 years of rituximab treatment. Rituximab has been evaluated in case series of patients with pulmonary rheumatoid nodules, resulting in most cases in no progression or a reduction in the size of the nodules, although the complete resolution is uncommon probably due to the short follow-up period. Complete disappearance of pulmonary rheumatoid nodules may be expected after long-term treatment with rituximab. © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Citation

Beatriz Frade-Sosa, Ana Belen Azuaga, Virginia Ruiz-Esquide, José A Gómez-Puerta, Raimon Sanmarti. Complete disappearance of pulmonary rheumatoid nodules after long term rituximab treatment: case report. Rheumatology international. 2023 Mar;43(3):533-536