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    Stent-induced ductal change (SIDC) is a complication of endoscopic pancreatic stenting (EPS) in patients with chronic pancreatitis (CP). However, the evaluation of SIDC associated with S-type pancreatic plastic stent (PS) and large-caliber PS, such as 10 Fr, is limited. This study aimed to analyze the SIDC of the main pancreatic duct (MPD) associated with 10-Fr S-type PS in patients with CP. Between January 2008 and December 2021, 132 patients with CP in whom a 10-Fr S-type PS had been installed by EPS were retrospectively reviewed. The SIDC incidence rate was examined, and the clinical features of patients with and without SIDC were investigated, including the outcomes for detected SIDC. Stent-induced ductal change during EPS was confirmed in 41 patients (31.1%) of 132 patients at a site coincident with the PS tip or distal flap in the MPD. All patients were asymptomatic during the development of SIDC. Morphological changes in the MPD were detected as elevated (75.6%) or bearing stricture changes (24.4%). A total of 90.2% of SIDC developed after the first 10-Fr PS installation. No significant differences were noted between the patients with and without SIDC. The outcomes of continued PS installment for SIDC showed persistence and secondary change. Stent-induced ductal change-associated 10-Fr PS installation was performed in just under one-third of the patients, indicating a substantial incidence rate and a possible development of SIDC from early stages onwards. More emphasis should be placed on SIDC as the complication. © 2022 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.


    Kensuke Takuma, Naoki Okano, Ken Ito, Wataru Ujita, Shuntaro Iwata, Saori Mizutani, Hiroki Nakagawa, Koji Watanabe, Yuto Yamada, Yusuke Kimura, Kensuke Yoshimoto, Susumu Iwasaki, Seiichi Hara, Yui Kishimoto, Yoshinori Igarashi, Takahisa Matsuda, Kazuki Amemiya. Focal pancreatic ductal change induced by 10-Fr S-type plastic stent in chronic pancreatitis. Journal of gastroenterology and hepatology. 2023 Jan;38(1):112-118

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    PMID: 36334302

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