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    Prenol and isoprenoids are common structural motifs in biological systems and possess diverse applications. An unprecedented direct catalytic prenylation of ketones using prenol is attained. This C-C bond formation reaction requires only a ruthenium pincer catalyst and a base, and H2O is the only byproduct.

    Citation

    Raman Vijaya Sankar, Deepsagar Manikpuri, Chidambaram Gunanathan. Ruthenium-catalysed α-prenylation of ketones using prenol. Organic & biomolecular chemistry. 2023 Jan 04;21(2):273-278

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    PMID: 36374234

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