Metal-dependent glycosylation in recombinant metallothioneins.

We show for the first time glycosylation of recombinant metallothioneins (MTs) produced in E. coli. Interestingly, our results show that the glycosylation level of the recombinant MTs is inversely proportional to the degree of protein structuration, and reflects their different metal preferences.

Citation

Mario García-Risco, Ana González, Sara Calatayud, Francisco J Lopez-Jaramillo, Veronika Pedrini-Martha, Ricard Albalat, Reinhard Dallinger, José M Dominguez-Vera, Òscar Palacios, Mercè Capdevila. Metal-dependent glycosylation in recombinant metallothioneins. Chemical communications (Cambridge, England). 2022 Dec 13;58(99):13755-13758

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PMID: 36416731

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