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IRF2 integrates inflammatory signals to balance T cell exhaustion.
Immunity 2022 Dec 13Sizes of these terms reflect their relevance to your search.
The transcription factor interferon regulatory factor 2 (IRF2) translates interferon signaling to regulate T cells. In this issue of Immunity, Lukhele et al. identify IRF2 in tumor-infiltrating T cells as a sensor for extrinsic signals that drives an exhaustion program. Copyright © 2022 Elsevier Inc. All rights reserved.
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Amania A Sheikh, Daniel T Utzschneider. IRF2 integrates inflammatory signals to balance T cell exhaustion. Immunity. 2022 Dec 13;55(12):2225-2227
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PMID: 36516816
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