Cardiac Imaging in Childhood Cancer Survivors: A State-of-the-Art Review.

Childhood cancer survival has improved significantly in the past few decades, reaching rates of 80% or more at 5 years. However, with improved survival, early- and late-occurring complications of chemotherapy and radiotherapy exposure are becoming progressively more evident. Cardiovascular diseases represent the leading cause of non-oncological morbidity and mortality in this highly vulnerable population. Therefore, the necessity of reliable, noninvasive screening tools able to early identify cardiac complications early is now pre-eminent in order to implement prevention strategies and mitigate disease progression. Echocardiography, may allow identification of myocardial dysfunction, pericardial complications, and valvular heart diseases. However, additional imaging modalities may be necessary in selected cases. This manuscript provides an in-depth review of noninvasive imaging parameters studied in childhood cancer survivors. Furthermore, we will illustrate brief surveillance recommendations according to available evidence and future perspectives in this expanding field. Copyright © 2022 Elsevier Inc. All rights reserved.

Citation

Massimiliano Camilli, Roderick Skinner, Giulia Iannaccone, Giulia La Vecchia, Rocco Antonio Montone, Gaetano Antonio Lanza, Luigi Natale, Filippo Crea, Matteo Cameli, Marco Giuseppe Del Buono, Antonella Lombardo, Giorgio Minotti. Cardiac Imaging in Childhood Cancer Survivors: A State-of-the-Art Review. Current problems in cardiology. 2023 Apr;48(4):101544

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PMID: 36529231

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