Case Report: Burkholderia pseudomallei-Caused Sclerokeratitis.

Onsiri Thanathanee, Korawin Charoensuk, Yuwarat Uthairat, Suparat Laohapitakvorn, Orapin Anutarapongpan, Olan Suwan-Apichon

The American journal of tropical medicine and hygiene 2023 Feb 01

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This report is on a 45-year-old male patient without underlying disease who presented with a Burkholderia pseudomallei-caused keratoscleritis in his right eye. Slit-lamp examination revealed multiple, indistinct corneal infiltrations with subconjunctival/scleral abscesses. Corneal tissue culture was positive for B. pseudomallei and confirmed by mass spectrometry. The patient was treated with fortified ceftazidime, fortified gentamicin eyedrops, and intravenous ceftazidime injection. Penetrating keratoplasty, including intracameral ceftazidime injections, was undertaken due to corneal lesion worsening. Scleral debridement with subconjunctival ceftazidime injections were undertaken due to the progression of the scleral abscess. After 2 months, the corneal and scleral lesions were inactive, and the systemic and topical antibiotics were tapered. This is the first case report of B. pseudomallei-caused keratoscleritis with photography. The patient was seen in an endemic geographical area with multiple corneal infiltrations and subconjunctival/scleral abscess. Systemic and topical antibiotics accompanied with surgery should be considered.

Citation

Onsiri Thanathanee, Korawin Charoensuk, Yuwarat Uthairat, Suparat Laohapitakvorn, Orapin Anutarapongpan, Olan Suwan-Apichon. Case Report: Burkholderia pseudomallei-Caused Sclerokeratitis. The American journal of tropical medicine and hygiene. 2023 Feb 01;108(2):293-295