Dead space fraction for treatment guidance and prognosis evaluation of acute respiratory distress syndrome].

Siqing Ma, Zhijian Wang, Litao Guo

Zhonghua wei zhong bing ji jiu yi xue 2022 Dec

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Acute respiratory distress syndrome (ARDS) is a common cause of critical illness and high mortality from respiratory failure. Increased dead space fraction (VD/VT) was independently associated with lung injury and mortality of ARDS. VD/VT is readily obtained by bedside measurements of arterial blood gas and end-tidal carbon dioxide. Early attention and application of VD/VT as an indicator will help to better understand the pathophysiological of ARDS, guide clinical treatment, and better assess the severity and clinical prognosis of the disease.

Citation

Siqing Ma, Zhijian Wang, Litao Guo. Dead space fraction for treatment guidance and prognosis evaluation of acute respiratory distress syndrome]. Zhonghua wei zhong bing ji jiu yi xue. 2022 Dec;34(12):1333-1336