Duration of Clinical Response After In-Office Steroid Injection for Vocal Fold Scar.

To assess the duration of clinical response after in-office vocal fold steroid injection (VFSI) for vocal fold (VF) scar. Demographic and clinical data for in-office VFSI occurring from 2017 to 2020 were collected. Two Speech-Language Pathologists (SLPs) used perceptual evaluation of voice and functional scales to evaluate blinded voice and laryngovideostroboscopy (LVS) samples collected pre- and post-injection across multiple timepoints. Blinded SLP ratings were used for 30 individual VFs undergoing initial injection in 18 patients. Persistent improvement in voice past 6 months was seen in 57% of patients after VFSI. Multiple measures of voice and amplitude, percent vibrating tissue, and closed phase predominance significantly improved at various follow-up timepoints on average. Accounting for patient heterogeneity and disease progression, in-office VFSI for VF scar is associated with sustained improvement in a subset of patients. Approximately half of patients can expect to experience a lasting improvement in voice. Future studies of larger scale are required to identify patient factors associated with long-term benefit. 4 Laryngoscope, 133:2333-2339, 2023. © 2023 The American Laryngological, Rhinological and Otological Society, Inc.

Citation

Lucas G Axiotakis, Necati Enver, Evan L Kennedy, Kimberly A Duncan, Michael J Pitman. Duration of Clinical Response After In-Office Steroid Injection for Vocal Fold Scar. The Laryngoscope. 2023 Sep;133(9):2333-2339

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PMID: 36594519

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