Intraoperative Management of an Orthotopic Porcine-to-Human Cardiac Xenotransplant.

We report the intraoperative management of an orthotopic cardiac xenotransplant in a 57-year-old man with nonischemic cardiomyopathy requiring venoarterial extracorporeal membrane oxygenation. Transesophageal echocardiography was used for preharvest assessment. Continuous ex vivo perfusion of the heart was performed. Steps were taken to avoid potential xenozoonosis transmission to other patients and staff. Preclinical experience guided our intraoperative management in controlling hemodynamics and using prophylactic antiarrhythmic medications. Echocardiography aided in the diagnosis of aortic dissection in the patient after transplant. Intraoperative cardiac function was excellent. The patient was weaned from all mechanical support 4 days after transplant. Copyright © 2023 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Citation

Erik R Strauss, Patrick N Odonkor, Brittney Williams, Seung Choi, Jaclyn Mueller, Bradley Taylor, Aakash Shah, Corbin E Goerlich, Muhammad M Mohiuddin, Bartley P Griffith. Intraoperative Management of an Orthotopic Porcine-to-Human Cardiac Xenotransplant. The Annals of thoracic surgery. 2023 Mar;115(3):784-786

Mesh Tags

PMID: 36621667

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