Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT.

Pavan Brahmbhatt, Fatemeh Ataei, Ephraim E Parent, Akash Sharma

Clinical nuclear medicine 2023 Mar 01

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Brown fat activation with increased radiotracer localization on FDG PET/CT studies is a well-known phenomenon. Activated brown adipose tissue (BAT) is usually seen in the supraclavicular region, but also in paraspinal and rarely in upper abdominal fat. Ours is a unique case of atypically intense, multilobular FDG uptake in activated BAT. Chart review revealed that the patient was receiving mirabegron, a known activator of brown fat. Methods of reducing brown fat uptake are known, but little information is reported on pharmacologic causes of increased uptake. Factors increasing FDG uptake in BAT should also be considered when interpreting PET/CT studies. Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.

Citation

Pavan Brahmbhatt, Fatemeh Ataei, Ephraim E Parent, Akash Sharma. Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT. Clinical nuclear medicine. 2023 Mar 01;48(3):233-236