Calcium imaging is a widely used imaging method to measure neuronal activity. In recent years, various highly sensitive and fast genetically encoded calcium indicators have been developed. Moreover, by utilizing these sensors with a multiphoton microscope and a microendoscope, it is possible to simultaneously measure the neural activity from multiple neurons with single-cell resolution in living animals. In this review, I will introduce features of fluorescent calcium probes and their application in vivo.
Masayuki Sakamoto. Measuring Neural Activity Using Calcium Indicators]. Brain and nerve = Shinkei kenkyu no shinpo. 2023 Feb;75(2):159-165
PMID: 36750214
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