Successful outcome in a compound heterozygote haemoglobin E/beta-thalassaemia in pregnancy.

Kalika Dubey, Charu Sharma, Suma Shet, Shashank Shekhar

BMJ case reports 2023 Feb 07

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Haemoglobin E (HbE) affects at least 1 million people around the world. The carrier frequency of HbE/beta-thalassaemia (HbE/β-thalassaemia) is highest in Southeast Asia. In India, the highest frequency is observed in the northeast region. Distinguishing between homozygous HbE disease and HbE/β-thalassaemia is a challenge to the haematopathologist as well as to the treating obstetrician because both are clinically and haematologically similar, posing a difficulty in managing anaemia and assessing the fetal risk for the same disease. This article reports a case of compound heterozygote HbE/β-thalassaemia in pregnancy and its successful outcome. © BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.

Citation

Kalika Dubey, Charu Sharma, Suma Shet, Shashank Shekhar. Successful outcome in a compound heterozygote haemoglobin E/beta-thalassaemia in pregnancy. BMJ case reports. 2023 Feb 07;16(2)