Pregnancy-induced severe hypertriglyceridemia effectively treated with therapeutic plasmapheresis.

Hypertriglyceridemia is associated with significant morbidity during pregnancy. Hypertriglyceridemia-induced pancreatitis (HTGP) is associated with genetically determined dyslipidemia or a secondary condition such as diabetes, alcohol, pregnancy, or medication use. The lack of data on the safety of drugs to be used to decrease triglyceride levels during pregnancy dictates that other strategies must be chosen. We describe a case of a pregnant woman with severe hypertriglyceridemia treated with two different techniques of plasmapheresis (Dual Filtration apheresis and Centrifugal Plasma Separation). The patient could be treated throughout the pregnancy, with good control of the triglycerides, and a healthy baby was born. Hypertriglyceridemia is a major issue during pregnancy. The use of plasmapheresis is a safe and efficient tool in that clinical scenario. Copyright © 2023 Elsevier Ltd. All rights reserved.

Citation

Gustavo de Carvalho Duarte, Lauren Farnden, Ruth C E Hughes, Huan Chan. Pregnancy-induced severe hypertriglyceridemia effectively treated with therapeutic plasmapheresis. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 2023 Jun;62(3):103659

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PMID: 36804190

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