Pregnancy and chronic renal failure: what is new in 2023?

Nima Vakilzadeh, Hélène Legardeur, David Desseauve, Olivier Phan

Revue medicale suisse 2023 Mar 01

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Chronic renal failure (CRF) during pregnancy increases the risk of fetomaternal complications such as preeclampsia, premature delivery and, above all, a deterioration of renal function. A multidisciplinary preconceptional assessment is necessary in this complex clinical situation. Progress in neonatal resuscitation and a better understanding of the pathophysiological mechanisms of autoimmune nephropathy have improved the prognosis of these high-risk pregnancies. This article provides an overview of the issues related to the follow-up of pregnant women with renal disease. It summarizes the glomerular and hemodynamic physiological changes during pregnancy, the fetal and maternal risk, and the adaptation of antihypertensive and immunosuppressive drug treatments.

Citation

Nima Vakilzadeh, Hélène Legardeur, David Desseauve, Olivier Phan. Pregnancy and chronic renal failure: what is new in 2023? Revue medicale suisse. 2023 Mar 01;19(816):401-405