Subcutaneous testosterone pellet therapy for reversal of male osteoporosis: a review and case report.

To describe the effects of consistent levels of testosterone in a pellet form and it's potential to reverse osteoporosis. This is a descriptive case report of a 54 year male with a spontaneous fracture and osteoporosis in the presence of what many consider a normal male testosterone level. After discovering and documenting osteoporosis by DXA scan, the patient was shown to reverse the diagnosis of osteoporosis in a year on pelleted testosterone therapy. Consistent levels of 943 ng/dL were achieved; the patient also experienced improvements in quality of life and sleep apnea. Testosterone deficiency (TD) is a clinical syndrome and osteoporosis can be found in levels above standard "criteria" of 300. This patient did not realize a benefit on injections both physical and clinically and both improved on pelleted testosterone. This should be further studied and considered for TD in men.

Citation

Bruce Dorr, Ahmed Abdelaziz, Mickey Karram. Subcutaneous testosterone pellet therapy for reversal of male osteoporosis: a review and case report. The aging male : the official journal of the International Society for the Study of the Aging Male. 2023 Dec;26(1):2181953

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PMID: 36912031

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