Nickel-catalyzed reductive coupling of arylcarboxylic acid 2-pyridyl esters with alkyl methanesulfonates: access to alkyl aryl ketones.

Alkyl aryl ketones were synthesized via a nickel-catalyzed reductive coupling reaction of arylcarboxylic acid (2-pyridyl)esters with primary and secondary alkyl methanesulfonates under mild reaction conditions. This method suits a wide range of substrates and shows good compatibility with functional groups.

Citation

Hang Yu, Zhong-Xia Wang. Nickel-catalyzed reductive coupling of arylcarboxylic acid 2-pyridyl esters with alkyl methanesulfonates: access to alkyl aryl ketones. Organic & biomolecular chemistry. 2023 Apr 26;21(16):3423-3431

PMID: 37021714

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