Correlation Engine 2.0
Clear Search sequence regions

  • aneurysms (8)
  • blood test (5)
  • humans (1)
  • patients (1)
  • screen (1)
  • Sizes of these terms reflect their relevance to your search.

    Intracranial aneurysms are reported to affect 2-5% of the population. Despite advances in the surgical management of this disease, diagnostic technologies have marginally improved and still rely on expensive or invasive imaging procedures. Currently, there is no blood-based test to detect cerebral aneurysm formation or quantify the risk of rupture. The aim of this review is to summarize current literature on the mechanism of aneurysm formation, specifically studies relating to inflammation, and provide a rationale and commentary on a hypothetical future blood-based test. Efforts should be focused on clinical-translational approaches to create an assay to screen for cerebral aneurysm presence and risk-stratify patients to allow for superior treatment timing and management. Cerebral Aneurysm Blood Test Considerations: There are multiple caveats to development of a putative blood test to detect cerebral aneurysm presence. © 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.


    Kamil W Nowicki, Aditya M Mittal, Hussam Abou-Al-Shaar, Emma K Rochlin, Michael J Lang, Bradley A Gross, Robert M Friedlander. A Future Blood Test to Detect Cerebral Aneurysms. Cellular and molecular neurobiology. 2023 Aug;43(6):2697-2711

    Expand section icon Mesh Tags

    PMID: 37046105

    View Full Text