Role of apolipoproteins in the pathogenesis of obesity.

Mingjing Huang, Jingyi Zheng, Lijun Chen, Sufang You, Huibin Huang

Clinica chimica acta; international journal of clinical chemistry 2023 May 01

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Obesity is a state presented by excessive accumulation and abnormal distribution of body fat, with metabolic disorders being one of its distinguishing features. Obesity is associated with dyslipidemia and apolipoproteins are important structural components of plasma lipoproteins. Apolipoproteins influence the progression of obesity by a variety of mechanisms including lipid metabolism, energy expenditure and inflammatory response. In this review, we discuss the role of apolipoproteins in obesity, mechanisms of action as well as their potential as new therapeutic targets. Copyright © 2023 Elsevier B.V. All rights reserved.

Citation

Mingjing Huang, Jingyi Zheng, Lijun Chen, Sufang You, Huibin Huang. Role of apolipoproteins in the pathogenesis of obesity. Clinica chimica acta; international journal of clinical chemistry. 2023 May 01;545:117359