Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses.
Sarath Kumar Thayallath, Sachin M Shet, Meena Bisht, Pranav Bharadwaj, Matheus M Pereira, Gregory Franklin, S K Nataraj, Dibyendu Mondal
Chemical communications (Cambridge, England) 2023 May 11Herein, we present a simple approach to fabricate protein nanoconstructs by complexing cytochrome C (Cyt C) with silk nanofibrils (SNF) and choline dihydrogen phosphate ionic liquid (IL). The peroxidase activity of the IL modified Cyt C nanoconstruct (Cyt C + SNF + IL) increased significantly (2.5 to 10-fold) over unmodified Cyt C and showed enhanced catalytic activity and stability under harsh conditions, proving its potential as a suitable protein packaging strategy.
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Sarath Kumar Thayallath, Sachin M Shet, Meena Bisht, Pranav Bharadwaj, Matheus M Pereira, Gregory Franklin, S K Nataraj, Dibyendu Mondal. Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses. Chemical communications (Cambridge, England). 2023 May 11;59(39):5894-5897
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PMID: 37097129
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