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Therapeutic options for patients with relapsed SCLC are limited, and the prognosis in this setting remains poor. While clinical outcomes for frontline treatment have modestly improved with the introduction of immunotherapy, treatment in the second-line setting persists almost unchanged. In this review, current treatment options and recent advances in molecular biology are described. Emerging therapeutic options in this setting, and potential strategies to improve clinical outcomes of these patients are also addressed. Copyright © 2023 Elsevier B.V. All rights reserved.

Citation

Laura Moliner, Bingnan Zhang, Giuseppe Lamberti, Andrea Ardizzoni, Lauren A Byers, Raffaele Califano. Novel therapeutic strategies for recurrent SCLC. Critical reviews in oncology/hematology. 2023 Jun;186:104017

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PMID: 37150311

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