The Role of Selected Adipocytokines in Ovarian Cancer and Endometrial Cancer.

Sebastian Stępień, Paweł Olczyk, Joanna Gola, Katarzyna Komosińska-Vassev, Aleksandra Mielczarek-Palacz

Cells 2023 Apr 09

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Due to their multidirectional influence, adipocytokines are currently the subject of numerous intensive studies. Significant impact applies to many processes, both physiological and pathological. Moreover, the role of adipocytokines in carcinogenesis seems particularly interesting and not fully understood. For this reason, ongoing research focuses on the role of these compounds in the network of interactions in the tumor microenvironment. Particular attention should be drawn to cancers that remain challenging for modern gynecological oncology-ovarian and endometrial cancer. This paper presents the role of selected adipocytokines, including leptin, adiponectin, visfatin, resistin, apelin, chemerin, omentin and vaspin in cancer, with a particular focus on ovarian and endometrial cancer, and their potential clinical relevance.

Citation

Sebastian Stępień, Paweł Olczyk, Joanna Gola, Katarzyna Komosińska-Vassev, Aleksandra Mielczarek-Palacz. The Role of Selected Adipocytokines in Ovarian Cancer and Endometrial Cancer. Cells. 2023 Apr 09;12(8)