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A 24-year-old man was admitted to our hospital because of severe heart failure. Although he was treated with diuretics and positive inotropic agents, his heart failure progressed. An endomyocardial biopsy revealed iron deposition in his myocytes. Finally, he was diagnosed with hereditary hemochromatosis. After starting administration of an iron-chelating agent in addition to conventional treatment for heart failure, his condition improved. We should consider hemochromatosis in heart failure patients with severe right ventricular dysfunction in addition to left ventricular dysfunction.

Citation

Akito Setoguchi, Hiroaki Kawano, Shinji Okano, Tomohiro Honda, Takeharu Kato, Sumito Dateki, Akira Senoo, Yomi Nakashima, Tetsufumi Motokawa, Yuki Ueno, Ryohei Akashi, Tsuyoshi Yonekura, Eijun Sueyoshi, Satoshi Ikeda, Yasushi Miyazaki, Koji Maemura. An Iron-chelating Agent Improved the Cardiac Function in a Patient with Severe Heart Failure Due to Hereditary Hemochromatosis. Internal medicine (Tokyo, Japan). 2023 May 17


PMID: 37197964

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