In this issue of Molecular Cell, Yang and colleagues1 discover age-dependent increases in broad regions of the repressive histone modification H3K27me3. They also demonstrate partial reversion to younger H3K27me3 patterns and gene expression upon resection of older livers. Copyright © 2023 Elsevier Inc. All rights reserved.
Elizabeth Ann Pollina, Eric Lieberman Greer. Prometheus unshackled: Liver regeneration makes you young. Molecular cell. 2023 May 18;83(10):1546-1548
PMID: 37207622
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