Photoexcited NiII-Aryl Complex-Mediated Giese Reaction of Aryl Bromides.

Xian-Chen He, Ke-Rong Li, Jie Gao, Jian-Ping Guan, Hong-Bin Chen, Hao-Yue Xiang, Kai Chen, Hua Yang

Organic letters 2023 Jun 09

filter terms:

A Giese reaction of aryl bromides with electron-deficient alkenes was developed, enabled by a dual catalyst system containing NiII complex and IrIII photocatalyst. This protocol could accommodate a variety of aryl bromides and electron-deficient alkenes, delivering the conjugate adducts in up to 97% yield. The utilization of photoexcited (dtbbpy)NiII(aryl)Br intermediate as an aryl radical source allows this novel transformation of aryl halides, thus expanding the chemical space of excited nickel catalysis.

Citation

Xian-Chen He, Ke-Rong Li, Jie Gao, Jian-Ping Guan, Hong-Bin Chen, Hao-Yue Xiang, Kai Chen, Hua Yang. Photoexcited NiII-Aryl Complex-Mediated Giese Reaction of Aryl Bromides. Organic letters. 2023 Jun 09;25(22):4056-4060