B cell depletion is becoming a preferred long-term treatment even in early multiple sclerosis, but concerns about the risks of impaired immune competence persist. In their observational study Schuckmann et al. thoroughly assessed the impact of B cell-adapted extended interval dosing on immunoglobulin levels as a surrogate of adverse immunosuppressive effects. Copyright © 2023 Elsevier Inc. All rights reserved.
Tradite Neziraj, Ludwig Kappos, Anne-Katrin Pröbstel. Moving toward personalized B cell depletion in multiple sclerosis? Med (New York, N.Y.). 2023 Jun 09;4(6):344-346
PMID: 37301194
View Full Text