Is 'Autologous sticky-bone' better than a simple mixture of autologous PRF and bioactive glass in the regeneration of human periodontal intra-bony defects? An extensive clinical and CBCT study.

Periodontal intra-bony defects (IBD) are commonly encountered in dental office and usually treated by open flap debridement (OFD) with/without bone grafts and/or GTR/PRF/other additives. One common problem remains with these measures is of 'solid space maintenance' at the determined location. In this report, autologous sticky bone (ASB) was used and compared to a simple mixture of PRF-bone graft (PRF-BG) to assess its regenerative potential in IBD, as the sticky bone is known to maintain the solid space by previous research. 21 IBD were treated either by OFD or PRF-BG mixture or ASB. Regenerative assessment was done clinically and radiographically by CBCT at 1-year. All the treatment modalities (OFD, PRF-BG, ASB) showed statistically significant improvements clinically and radiographically at 1-year in terms of probing pocket depth reduction, clinical attachment level gain, CBCT defect fill and CBCT defect resolution (P<0.05). Out of these ASB group depicted most favourable results (P<0.05) in terms of above-mentioned parameters at 1-year followed by PRF-BG group and then OFD group. Treatment of periodontal IBD with autologous sticky bone resulted in significant improvements of clinical and CBCT parameters compared to baseline at 1-year. Also, the intra-surgical graft handling was extremely better in ASB group. Int J Periodontics Restorative Dent. doi: 10.11607/prd.6152.

Citation

Neelesh Singh, Medha Kashyap. Is 'Autologous sticky-bone' better than a simple mixture of autologous PRF and bioactive glass in the regeneration of human periodontal intra-bony defects? An extensive clinical and CBCT study. The International journal of periodontics & restorative dentistry. 2023 Jun 13

PMID: 37310376

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