Novelties on the management of alveolar echinococcosis].

Gaëtan-Romain Joliat, Didier Roulin, Ismail Labgaa, Emilie Uldry, Nicolas Demartines, Nermin Halkic, Emmanuel Melloul

Revue medicale suisse 2023 Jun 14

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Alveolar echinococcosis is an endemic parasitosis in Switzerland. This pathology mainly infects the liver and develops similarly as a malignant tumor with its ability to spread into the hepatic parenchyma and its capacity of developing distant lesions via hematogenous dissemination. Treatment is based on complete surgical resection coupled with albendazole treatment. Recently, ex vivo liver resections with auto-transplantation have been shown to be feasible in case of end-stage alveolar echinococcosis. Moreover, new biomarkers such as programmed death-ligand 1 (PD-L1), a protein with immunomodulation property, have shown their potential impact on the treatment and follow-up of patients with alveolar echinococcosis.

Citation

Gaëtan-Romain Joliat, Didier Roulin, Ismail Labgaa, Emilie Uldry, Nicolas Demartines, Nermin Halkic, Emmanuel Melloul. Novelties on the management of alveolar echinococcosis]. Revue medicale suisse. 2023 Jun 14;19(831):1192-1195