Bilateral Adrenal Infarction That Developed in Latent Essential Thrombocythemia.

Yurika Hada, Akane Yamada, Takuya Kobayashi, Takuma Sugiyama, Kota Ishii, Kaoru Takase, Noe Takakubo, Kyoko Nagaoka, Shigeru Karasawa, Wataru Kameda, Kenichi Ishizawa, Shinji Susa

Internal medicine (Tokyo, Japan) 2024 Feb 01

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Bilateral adrenal infarction is an extremely rare disease, and it has been reported that some coagulation abnormalities, including essential thrombocythemia (ET), exist in the background. We herein report a 76-year-old patient in whom the platelet count had been in the normal range at the onset of adrenal infarction but subsequently increased to 102×104/μL at 7 months later, leading to the diagnosis of JAK2V617F-positive ET. As the presence of the JAK2V617F mutation increases the risk of thrombosis, Janus kinase 2 (JAK2) genetic testing should be considered in some cases of nonspecific unknown thrombosis, even if there are no obvious hematological findings, such as clonal hematopoiesis of indeterminate potential (CHIP).

Citation

Yurika Hada, Akane Yamada, Takuya Kobayashi, Takuma Sugiyama, Kota Ishii, Kaoru Takase, Noe Takakubo, Kyoko Nagaoka, Shigeru Karasawa, Wataru Kameda, Kenichi Ishizawa, Shinji Susa. Bilateral Adrenal Infarction That Developed in Latent Essential Thrombocythemia. Internal medicine (Tokyo, Japan). 2024 Feb 01;63(3):419-423