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We report a computational model for amyloid fibrils and discuss its main features and ability to match different experimental morphological characteristics. The model captures the liquid crystalline and cholesteric behaviours in short and rigid amyloid fibrils and shows promising extendibility to more complex colloidal liquid crystals.


Shaden M Daghash, Oscar M Matus Rivas, Raffaele Mezzenga, Alejandro D Rey. A coarse-grained molecular model of amyloid fibrils systems. Soft matter. 2023 Jul 12;19(27):5044-5049

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PMID: 37395483

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