Characterization of a strain-specific CD-1 reference genome reveals potential inter- and intra-strain functional variability

CD-1 is an outbred mouse stock that is frequently used in toxicology, pharmacology, and fundamental biomedical research. Although inbred strains are typically better suited for such studies due to minimal genetic variability, outbred stocks confer practical advantages over inbred strains, such as improved breeding performance and low cost. Knowledge of the full genetic variability of CD-1 would make it more useful in toxicology, pharmacology, and fundamental biomedical research.

Citation

Yoon Hee Jung, Hsiao-Lin V. Wang, Samir Ali, Victor G. Corces, Isaac Kremsky. Characterization of a strain-specific CD-1 reference genome reveals potential inter- and intra-strain functional variability BMC Genomics. 2023 Aug 03;24

PMID: 37537522

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