Antioxidant and Renin Inhibitory Activities of Peptides from Food Proteins on Hypertension: A Review.

Plant foods for human nutrition (Dordrecht, Netherlands) 2023 Sep

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Hypertension is a condition induced by oxidative stress causing an alteration in the endothelium, which increases the risk of suffering from other degenerative diseases. This review compiles the findings on peptides from food proteins with antioxidant and antihypertensive activities. Antihypertensive peptides are mainly focused on renin inhibition. Peptides containing hydrophobic amino acids have antioxidant and renin inhibitory activities, as reported by studies on the biological activity of peptides from various food sources evaluated separately and simultaneously. Peptides from food sources can present multiple biological activities. Moreover, antioxidant peptides have the potential to be evaluated against renin, offering an alternative for hypertension therapy without causing adverse side effects. © 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Citation

Deyanira Del Rosario Moguel-Concha, José Eduardo Borges-Martínez, María Stephanie Cid-Gallegos, Milagros Faridy Juárez-Chairez, Ana Luisa Gómez-Gómez, Darío Iker Téllez-Medina, Cristian Jiménez-Martínez. Antioxidant and Renin Inhibitory Activities of Peptides from Food Proteins on Hypertension: A Review. Plant foods for human nutrition (Dordrecht, Netherlands). 2023 Sep;78(3):493-505