Functional Diversity of SIRT7 Across Cellular Compartments: Insights and Perspectives.

Songtao Wu, Shengnan Jia

Cell biochemistry and biophysics 2023 Sep

filter terms:

Posttranslational modifications (PTMs) play important roles in the regulation of protein function. Acetylation and deacetylation are among the most important PTMs. SIRT7 is a relatively understudied member of the sirtuin family, but recent studies have revealed that it plays a regulatory role in a variety of cellular activities, such as genome stabilization and repair, gene translation, ribosome production and other important processes. Here, we provide a list of the functions and mechanisms of SIRT7 in various organelles and show the important role of SIRT7 in maintaining normal cell function. © 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Citation

Songtao Wu, Shengnan Jia. Functional Diversity of SIRT7 Across Cellular Compartments: Insights and Perspectives. Cell biochemistry and biophysics. 2023 Sep;81(3):409-419