Direct or Indirect Action Mechanisms of Naringin in Maintaining Bone Homeostasis.

Xianghu Zhao, Jing Hu, Jie Liu, Yi Meng, Xiangzhong Liu, Haijia Xu, Yu Ning, Zhanghua Li

Cellular and molecular biology (Noisy-le-Grand, France) 2023 Jun 30

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Disruption of bone homeostasis is the pathological basis of bone diseases. Multiple cells work together to maintain homeostasis and bone health. As a natural flavonoid compound, Naringin (NG) can positively affect the maintenance of bone homeostasis by acting on different types of cells. In this review, we discuss the direct and indirect osteoprotective effects of NG as well as the underlying mechanisms, and we provide a critical perspective on its clinical translation.

Citation

Xianghu Zhao, Jing Hu, Jie Liu, Yi Meng, Xiangzhong Liu, Haijia Xu, Yu Ning, Zhanghua Li. Direct or Indirect Action Mechanisms of Naringin in Maintaining Bone Homeostasis. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Jun 30;69(6):151-159