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Potassium disorders are one of the most common electrolyte abnormalities in patients with chronic kidney disease (CKD), contributing to poor clinical outcomes. Maintaining serum potassium levels within the physiologically normal range is critically important in these patients. Dietary potassium restriction has long been considered a core strategy for the management of chronic hyperkalemia in patients with CKD. However, this has been challenged by recent evidence suggesting a paradigm shift toward fostering more liberalized, plant-based dietary patterns. The advent of novel potassium binders and an improved understanding of gastrointestinal processes involved in potassium homeostasis (e.g., gastrointestinal potassium wasting) may facilitate a paradigm shift and incorporation of heart-healthy potassium-enriched food sources. Nevertheless, uncertainty regarding the risk-benefit of plant-based diets in the context of potassium management in CKD remains, requiring well-designed clinical trials to determine the efficacy of dietary potassium manipulation toward improvement of clinical outcomes in patients with CKD. Copyright © 2023 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Citation

Keiichi Sumida, Annabel Biruete, Brandon M Kistler, Ban-Hock Khor, Zarina Ebrahim, Rossella Giannini, Elizabeth J Sussman-Dabach, Carla Maria Avesani, Maria Chan, Kelly Lambert, Angela Yee-Moon Wang, Deborah J Clegg, Jerrilynn D Burrowes, Biff F Palmer, Juan-Jesus Carrero, Csaba P Kovesdy. New Insights Into Dietary Approaches to Potassium Management in Chronic Kidney Disease. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 2023 Nov;33(6S):S6-S12

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PMID: 37610407

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