Cobalt Species-Loaded MOFs as Chemiluminescent Catalysts for Monitoring Carbendazim.

The application of active metal-based nanoscale catalysts as signal enhancers for chemiluminescent immunoassay (CLIA) is restricted by poor thermodynamic stability and ease of aggregation. For the present exploration, zirconium-based MOFs UiO-66-NH2 were adopted as supports to load cobalt species by an impregnation-reduction approach. Cobalt species were uniformly distributed in the framework architecture of the MOF materials. The prepared cobalt-loaded MOF hybrids, noted as UiO-66-NH2/Co, display superior chemiluminescence (CL) catalytic activity owing to the introduction of cobalt catalytic centers. The CL catalytic capability of UiO-66-NH2/Co hybrids is about 18 times of that of free cobalt ions at the same cobalt amount. The results of mechanism exploration manifest that the hybrids are capable of accelerating the decay of hydrogen peroxide and promoting the yield of reactive oxygen species. Based on their remarkable CL catalytic capability, a CLIA approach was proposed to monitor carbendazim by adopting the hybrids as signal probes, which showed the merits of high sensitivity and satisfactory selectivity. Carbendazim was quantitated within a concentration range of 0.05 to 60 ng mL-1, with a detection limit of 19.8 pg mL-1. The results for monitoring spiked samples verify the acceptable practicality of the proposed CLIA approach.

Citation

Lvxia Zhang, Lingli Zhang, Jinxia Xue, Hongwei Yuan, Chunjie Zhou, Ting Guo, Lin Wang, Zhifeng Fu. Cobalt Species-Loaded MOFs as Chemiluminescent Catalysts for Monitoring Carbendazim. Langmuir : the ACS journal of surfaces and colloids. 2023 Sep 12;39(36):12785-12792

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PMID: 37643321

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