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For the CRISPR Fan(zor)atics: RNA-guided DNA endonucleases discovered in eukaryotes.
Molecular cell 2023 Sep 07Sizes of these terms reflect their relevance to your search.
RNA-guided DNA endonucleases such as those from CRISPR-Cas systems were considered limited to prokaryotes. Saito et al.1 reveal that distant eukaryotic relatives of Cas nucleases, called Fanzors, also function as RNA-guided DNA endonucleases and can be harnessed for genome editing. Copyright © 2023 Elsevier Inc. All rights reserved.
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Constantinos Patinios, Chase L Beisel. For the CRISPR Fan(zor)atics: RNA-guided DNA endonucleases discovered in eukaryotes. Molecular cell. 2023 Sep 07;83(17):3046-3048
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PMID: 37683609
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