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The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells. Copyright: © 2023 Cooper, Postovit. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation

Tyler T Cooper, Lynne-Marie Postovit. Wounding the stroma: Docetaxel's role in dormant breast cancer escape. PLoS biology. 2023 Sep;21(9):e3002297

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PMID: 37703292

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