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Immediate or delayed hypersensitivity reactions to iodinated contrast media (ICM) occur in 0.5-3 % of patients receiving radiological examinations using the last generation ICM. Although the majority of the reactions are mild to moderate, severe and potentially lethal reactions may occasionally be observed. In the last few years, there has been an increase of patients referred to the dermato-allergology department for the work-up of a hypersensitivity reaction to ICM. In this article, the allergological investigations and their indications are described in the case of a suspicion of ICM hypersensitivity.


Gilles Absil, Louise Vanhakendover, Mahmoud Baghaie, Arjen Nikkels, Bita Dezfoulian. How I explore … an hypersensitivity to iodinated contrast media]. Revue medicale de Liege. 2023 Sep;78(9):523-528

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PMID: 37712163

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